MSNS : R package for Mutli-source nons-specific hybridization model
History
- 2009/9/9: Version 0.9.0 Published
Table of Contents
- Introduction
- Download
- Reference
This model estimates effects of non-specific hybridization included in
observed probe intensity. It assumes that the amounts of
cross-hybridization on a probe can be estimated as an ensemble of
a diverse of fragments which randomly hybridize with the probe
non-specifically.
This package provids functions for the estimation of non-specific
hybridization and optimization of parameters used in the model.
How to install
For UNIX or MacOSX users
- Download the source package.
- Open R console,
setwd to the directory where the package was placed.
- Install package by
install.packages as follows,
> install.packages(pkgs="MSNS_0.9.0.tar.gz",repos=NULL,type="source")
For Windows users
- Sorry, precombiled package is not available at present. Please try to build from the source.
[1] C. Furusawa et al., "Model-based analysis of non-specific binding for background correction of high-density oligonucleotide microarrays", (in preparation).
[3] R: A Language and Environment for Statistical Computing, R Development Core Team (2007), Vienna, Austria. ISBN 3-900051-07-0.
[4] Bioconductor, The Bioconductor core team.
[5] GeneChip(R) system, Affymetrix.
Corresponding author: C. Furuswa and N. ONO. ({furusawa,nono} at bio.eng.osaka-u.ac.jp)