Shimizu Lab. Graduate School of Information Science and Technology,Osaka University

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Proceedings

2019

  1. Hiroshi Shimizu,"Integration of in silico Genetic Modification Design and Adaptive Laboratory Evolution to Increase in Productivity of Target Compounds", International Conference on Metabolic Science 2019, Golden Tulip Shanghai Rainbow Hotel, China, Nov20-23,2019, invited
  2. Hiroshi Shimizu, "Metabolic Engineering to Create Microbial Cell Factories", The 21st Academic Exchange Seminar Between Shanghai Jiao Tong University And Osaka University, 大阪大学工学研究科生命先端工学専攻5階サントリーメモリアルホール, Japan, Nov19, 2019, invited
  3. Yoshihiro Toya, "Light-inducible flux control of the central carbon metabolism in Escherichia coli", ASBA2019, JW Marriot Hotel Chengdu,China,Oct,26-30, 2019, invited
  4. Hiroshi Shimizu, ”In silico analysis and design of photosynthesis and metabolic pathways of Synechocystis sp. PCC6803”, 日米二国間セミナー, Kyoto International Community House, Japan, Oct1-3, 2019, invited
  5. Masakazu Toyoshima, Chiaki Yamamoto, Yoshifumi Ueno, Yoshihiro Toya, Seiji Akimoto, Hiroshi Shimizu,"FBA simulation of photosynthetic electron flow of Synechocystis sp. PCC 6803 under different spectral light condition", 日米二国間セミナー, Kyoto International Community House, Japan, Oct1-3, 2019
  6. Hiroshi Shimizu, "Integration of in silico and experimental approaches to create microbial cell factories", US-Japan Joint Workshop on Bioengineering and Information Science, San Diego, USA, Sep 9-10, 2019
  7. Hiroshi Shimizu, ”/In silico/ Metabolic Pathway Design and Experimental Flux Analysis for Creation of Microbial Cell Factory”, KMB 2019 46th Annual Meeting & International Symposium, International Convention Center Jeju, Jeju, Korea, Jun.23-25, 2019
  8. Hiroshi Shimizu, "Integration of in silico and experimental approaches for creation of microbial cell factories", 2019 KSBB Sprilng Meeting and International Symposium, Maisonglad Jeju Hotel, Jeju, Korea, Apr.10-12, 2019
  9.  Kento Maeda, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu, "Efficient mevalonic acid production in high cell density fed-batch culture of Escherichia coli ", iBioK, Kobe University, Japan, Jan 24-25, 2019

2018

  1. Hikaru Uehara, Chie Araki, Kousuke Maeda, Nobuyuki Okahashi, Fumio Matsuda, Hiroshi Shimizu, "13C-Metabolic flux analysis of the central carbon metabolism in three cancer cell lines", YABEC2018, National Taiwan University of Science & Technolog, Taipei, Republic of China, Nov. 15-17, 2018
  2. Hiroshi Shimizu, Systems Biology and Metabolic Engineering of Photosynthetic Organisms, International Symposium on Photosynthesis and Chloroplast Biogenesis 2018, Kurashiki Kokusai Hotel, Okayama, Japan, Nov 7-10, 2018, invited
  3. Masakazu Toyoshima, Yoshihiro Toya, Hiroshi Shimizu, "Relationship between PSI/PSII excitation ratio and photosynthetic electron transport of Synechocystis sp. PCC 6803 by FBA simulation", International Symposium on Photosynthesis and Chloroplast Biogenesis 2018, Kurashiki Kokusai Hotel, Okayama, Japan, Nov 7-10, 2018
  4. Hiroki Nishiguchi, Hikaru Nagai, Fumio Matsuda, Hiroshi shimizu, "Rational metabolic engineering of central metabolism in cyanobacteria using kinetic model ensemble",  International Symposium on Photosynthesis and Chloroplast Biogenesis 2018, Kurashiki Kokusai Hotel, Okayama, Japan, Nov 7-10, 2018
  5. Yuma Tokumaru, Masakazu Toyoshima, Fumio Matsuda, Hiroshi Shimizu, "Target phosphoproteome analysis of Synchocystis sp PCC 6803 using nano liquid chromatography- triple quadrupole mass spectrometry", International Symposium on Photosynthesis and Chloroplast Biogenesis 2018, Kurashiki Kokusai Hotel, Okayama, Japan, Nov 7-10, 2018
  6. Tokumaru Yuma, Masakazu Toyoshima, Fumio Matsuda, Hiroshi Shimizu,”Target phosphoproteome analysis of Synchocystis sp PCC 6803 using nano liquid chromatography- triple quadrupole mass spectrometry”,13th KAIST-OSAKA U Symposium 2018,Suntory Memorial Hall,Osaka University,Japan,Oct 19-21,2018
  7. Hiroki Nishiguchi, Hikaru Nagai, Fumio Matsuda, Hiroshi shimizu,"Dynamic modeling of central metabolism in cyanobacteria for improving ethanol production",13th KAIST-OSAKA U Symposium 2018,Suntory Memorial Hall,Osaka University,Japan,Oct 19-21,2018
  8. Kento Tokuyama, Yoshihiro Toya, Takaaki Horinouchi, Chikara Furusawa, Fumio Matsuda, Hiroshi Shimizu, " Expanding the space of actual metabolic network in Escherichia coli by adaptive laboratory evolutio" , Metabolic Engineering 12, The Westin Grand Munich, Munich, Germany, Jun 24-28,2018
  9. Naoya Nochino, Yoshihiro Toya, Hiroshi Shimizu, ''Elucidation of Metabolic Regulation Mechanism of Escherichia coli in Response to Oxygen Level'', Metabolic Engineering 12, The Westin Grand Munich, Munich, Germany, Jun 24-28,2018

2017

  1. Masakazu Toyoshima, Masumi Sakata, Kazuki Ohnishi, Yuma Tokumaru, Fumio Matsuda, Hiroshi Shimizu, ''Quantitative proteome analysis of microalgae under high light stress'', I-Bios2017, National University of Singapore, Singapore, Dec19-20, 2017
  2. Keisuke Morita, Fumio Matsuda, Jun Ishii, Akihiko Kondo, Hiroshi Shimizu, ''Dynamic regulation of ethanol production in yeast by inactive Cas9 system'', I-Bios2017, National University of Singapore, Singapore, Dec19-20, 2017
  3. Kento Tokuyama, Yoshihiro Toya, Takaaki Horinouchi, Chikara Furusawa, Fumio Matsuda, Hiroshi Shimizu,'' Expanding the space of actual metabolic network for growth-coupled succinate production in Escherichia coli by adaptive laboratory evolution'', YABEC2017, Jin Jiang International Hotel Xi’an, China, Oct18-20, 2017
  4. Tokuyama Kento, Sakai Tomofumi, Toya Yoshihiro, Matsuda Fumio, KuramitsuSeiki, Shimizu Hiroshi,  Metabolic profiling of ThermusthermophilusHB8 reveals distinct metabolic states dependent on the temperature,  IUMS2017, Marina Bay Sands Convention Centre, Singapore, Jul 17-21, 2017
  5. Tokuyama Kento, Toya Yoshihiro, Horinouchi Takaaki, Furusawa Chikara, Shimizu Hiroshi, ”Adaptive laboratory evolution of in silico designed succinate producing Escherichia coli”, IUMS2017, Marina Bay Sands Convention Centre, Singapore, Jul 17-21, 2017
  6. Fumio Matsuda, Yohei Yamada, Samik Ghosh, Takeshi Hase, Syohei  Kinoshita, Shunsuke Nishino, Atsumi Tomita,Nikolaos Tsorman,  Atsuhiko Toyama, Shigeki Kajihara2 Norio Mukai, Yukiko Matsuoka,  Hiroshi Shimizu, Eiichiro Fukisaki, Hiroaki Kitano, Junko Iida, ”Automated visualization of metabolome, proteome and fluxome data on  Garuda – a connectivity platform for biomedical analytics”, 65th ASMS Conference on Mass Spectrometry and Allied Topics, Indiana Convention Center, Indianapolis, USA, Jun 4-8, 2017
  7. Yoshihiro Toya, "Application of 13C-metabolic flux analysis for efficient mevalonate production in Escherichia coli",2017 Annual Symposium and General Meeting of Korea Metabolomics Society (KoMetS),Konkuk University New Millenium Hall, South Korea, Apr 5-6, 2017, invited

2016

  1. Yoshihiro Toya, Keisuke Wada, Ami Masuda, Kento Tokuyama, Satomi Banno, Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu,"Metabolic flux measurement for efficient mevalonate production in Escherichia coli",i-BioP2016, Haeundae Grand Hotel , Busan, South Korea, Dec 16-18, 2016
  2. Wada Keisuke, Uebayashi  Kiyoka, Toya Yoshihiro, Dempo Yudai, Putri Sastia, Matsuda Fumio, Fukusaki Eiichiro, Liao James and Shimizu Hiroshi, "Isotopically non-stationary 13C-metabolic flux analysis of n-butanol production in Synechococcus elongatus", i-BioP2016, Haeundae Grand Hotel , Busan, South Korea, Dec 16-18, 2016
  3. Ken-ichi Ogawa, Katsunori Yoshikawa, Fumio Matusuda, Yoshihiro Toya, Hiroshi Shimizu, ” Development of high-light stress tolerant strain of Synechocystis sp. PCC 6803 by adaptive evolution”, The 13th International Symposium on the Genetics of Industrial Microorganisms(GIM2016), East Lake Hotel, Wuhan, China, Oct 16-20, 2016, invited
  4. Hiroshi Shimizu, ”Integration of in silico design and experimental evaluation of metabolic pathways for creation of microbial cell factories”, International Conference on the Metabolic Science(ICMS 2016), Nanjiao Hotel, Shanghai China, Oct 20-23, 2016, invited
  5. Hiroshi Shimizu, ”13C-metabolic flux analysis for rational design of metabolic pathway modification of the industrially useful microorganisms”, The 13th International Symposium on the Genetics of Industrial Microorganisms(GIM2016), East Lake Hotel, Wuhan, China, Oct 16-20, 2016, invited
  6. Fumio Matsuda, "Transomics analysis of the central metabolism of Saccharomyces cerevisiae", The 14th International Congress on Yeasts, Awaji Yumebutai, Japan, Sep 11-15, 2016
  7. Keisuke Morita, Fumio Matsuda, Koji Okamoto, Kengo Ida, Jun Ishii, Akihiko Kondo, Hiroshi Shimizu, "Engineering of mitochondrial isobutanol production in Saccharomyces", The 14th International Congress on Yeasts, Awaji Yumebutai, Japan, Sep 11-15, 2016
  8. Fumio Matsuda, "Ensemble modeling of cyanobacteria metabolism using multi-omics data", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  9. Yoshihiro Toya, Ami Masuda, Takanori Shiraki, Hiroshi Shimizu, "Computational pathway design for efficient bio-production during stationary phase", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  10. Keisuke Morita, Fumio Matsuda, Koji Okamoto, Kengo Ida, Jun Ishii, Akihiko Kondo, Hiroshi Shimizu, "Engineering of mitochondrial isobutanol production in Saccharomyces cerevisiae", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  11. Kento Tokuyama, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu, "Effect of nutrients starvation on 3-hydroxypropionic acid production by recombinant Escherichia coli at stationary phase", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  12. Keisuke Morita, Fumio Matsuda, Jun Ishii, Akihiko Kondo, Hiroshi Shimizu, "Heterologous gene expression in Saccharomyces cerevisiae for higher isobutanol production", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  13. Kenshi Hayakawa, Fumio Matsuda, Hiroshi Shimizu,"13C-metabolic flux analysis of ethanol-assimilating Saccharomyces cerevisiae for S-adenosyl-L-methionine production", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  14. Wada Keisuke, Toya Yoshihiro, Matsuda Fumio, Shimizu Hiroshi, "13C-Metabolic Flux Analysis for Mevalonate-Producing Strain of Escherichia coli", Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  15. Nobuyuki Okahashi, Fumio Matsuda, Katsunori Yoshikawa, Tomokazu Shirai, Yoshiko Matsumoto, Mitsufumi Wada, Hiroshi Shimizu, "Metabolic Engineering for Upgrading Isopropyl Alcohol Production By Escherichia coli Based on 13c­Metabolic Flux Data",Metabolic Engineering 11, Awaji Yumebutai, Japan, Jun 26-30, 2016
  16. Fumio Matsuda, Syunsuke Nishino, Tairo Ogura, Atusmi Tomita, Ichiro Hirano, Hiroshi Shimizu, "Trans-omics Analysis of Yeast Central Carbon Metabolism by Integration of Metabolome, Proteome and Fluxome Data", 64th ASMS Conference, San Antonio, Texas, America, Jun 5-9, 2016
  17. Kenshi Hayakawa, Fumio Matsuda, Hiroshi Shimizu, "Metabolome analysis of S-adenosyl-L-methionine production by Saccharomyces cerevisiae",ICBE16, Grand Hyatt Singapore, Jan 5-7, 2016

2015

  1. Kento Tokuyama, Yoshihiro Toya, Shimizu Hiroshi," Effect of nutrient starvation on stationary phase for efficient 3-hydroxypropionic acid production in Escherichia coli " iBioK, Kobe University, Japan, Dec 7-8, 2015
  2. Nobuyuki Okahashi, Katsunori Yoshikawa, Yoshiko Matsumoto, Tomokazu Shirai, Fumio Matsuda, Mitsufumi Wada, Hiroshi Shimizu, ”13C-metabolic flux analysis of IPA-producing E. coli at growth and non-growth phases ” ,iBioK, Kobe University, Japan, Dec 7-8, 2015
  3. Kenta Masuda, Yoshihiro Toya, Shenghao Liu, Takuya Morimoto, Kazuhisa Sawada, Fumikazu Takahashi, Kenji Manabe, Yasushi Kageyama, Takashi Hirasawa, Ken-ichi Yoshida, Hiroshi Shimizu, Naotake Ogasawara, Katsuya Ozaki, Hiroshi Hagihara, ”Enhanced productions of bio-based chemicals by using Bacillus subtilis genome reduced strain as a platform cell factory”, 8th International Conference on Gram-Positive Microorganisms, Montecatini Terme, Tuscany, Italy, Jun 21-25, 2015
  4. Shenghao Liu, Yoshihiro Toya, Kenta Masuda, Takuya Morimoto, Yasushi Kageyama, Takashi Hirasawa, Hiroshi Shimizu, Naotake Ogasawara, Katsuya Ozaki, Hiroshi Hagihara, ’’Improvement of dipicolinic acid production of Bacillus subtilis genome reduced strain MGB874 based on 13C-metabolic flux analysis’’ , 8th International Conference on Gram-Positive Microorganisms, Montecatini Terme, Tuscany, Italy, Jun 21-25, 2015
  5. Hiroshi Shimizu,"In silico metabolic pathway design and 13C-based metabolic flux analysis for bio-production",The 2nd SBJ Symposium, Icho Kaikan,Osaka University, Japan, May 22, 2015, invited

2014

  1. Riyanto Heru Nugroho, Katsunori Yoshikawa, Hiroshi Shimizu, "Metabolic profiling of proline contribution for improving cell density in Saccharomyces cerevisiae", GIW / ISCB-Asia 2014, Dec 15-17, 2014
  2. Katsunori Yoshikawa, Fumio Matsuda, Hiroshi Shimizu, "Development of Systems Metabolic Engineering Tools for Cyanobacteria", AOAIS 2014, Nov 17-20, 2014, invited
  3. Natsuki Hiasa, Kenji Urai, Risa Sawada, Masashi Yokota, "Development of a Rajiform Robot as a Next Generation Bio-inspired Autonomous Underwater Vehicle", ISBAMEC2014, Nov 13-16, 2014
  4. Kento Tokuyama, Katsunori Yoshikawa, Chikara Furusawa, Hiroshi Shimizu, "Metabolic engineering of Escherichia coli for 3-hydroxypropionic acid production from glycerol based on the genome-scale metabolic simulation", KAIST workshop, Osaka University, Sep 22-24, 2014
  5. Nobuyuki Okahashi, Katsunori Yoshikawa, Yoshiko Matsumoto, Tomokazu Shirai, Fumio Matsuda, Takashi Hirasawa, Chikara Furusawa, Mitsufumi Wada and Hiroshi Shimizu, "Metabolic Evaluation of Isopropyl Alcohol-Producing Escherichia coli Using 13C-Metabolic Flux Analysis", KAIST workshop, Osaka University, Sep 22-24,2014
  6. Fumio Matsuda, Syunsuke Nishino, Tairo Ogura, Nobuyuki Okahashi, Atsumi Tomita, Ichiro Hirano, and Hiroshi Shimizu, "Integrated targeted metabolome and proteome analysis for dissecting energy metabolism in yeast", International Conference of Metabolomics Society, Tsuruoka, Japan, Jun 23-26,2014
  7. Syuichi Kajihata, Chikara Furusawa, Fumio Matsuda, Hiroshi Shimizu, "OpenMebius: An Open source software for Metabolic flux analysis", International Conference of Metabolomics Society, Tsuruoka, Japan, Jun 23-26,2014
  8. Riyanto Heru Nugroho, Katsunori Yoshikawa, Hiroshi Shimizu, "Metabolomics perspective of acid stress response within Saccharomyces cerevisiae", International Conference of Metabolomics Society, Tsuruoka, Japan, Jun 23-26,2014
  9. Nobuyuki Okahashi, Fumio Matsuda, Susumu Kohno, Chiaki Takahashi, Hiroshi Shimizu, "Reductive glutamine metabolism in p53-null soft tissue sarcoma cells", International Conference of Metabolomics Society, Tsuruoka, Japan, Jun 23-26,2014
  10. Shuichi Kajihata, Chikara furusawa, Fumio matsuda, Hiroshi Shimizu, "Metabolic flux analysis of Saccharomyces cerevisiae with a reduced Crabtree effect", International Conference of Metabolomics Society, Tsuruoka, Japan, Jun 23-26,2014
  11. Fumio Matsuda, Tairo Ogura, Nobuyuki Okahashi, Atsumi Tomita, Ichiro Hirano, and Hiroshi Shimizu, "Development of a nanoLC-MRM-based quantitative platform for multiple enzymes associated with the central metabolic pathway by using ultra-fast mass spectrometry", The 62nd Conferenc of American Socisety for Massspectrometry, Baltiomore Convention Center Baltimore MD, Jun 15-19,2014
  12. Kosei Tanaka, Yoshihiro Toya, Shinji Takenaka, Hiroshi Shimizu, and Ken-ichi Yoshida, "Bacterial cell factory for production of scyllo-inositol, a potential therapeutic agent for Alzheimer's disease", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014
  13. Yoshihiro Toya, Takashi Hirasawa, Kenta Masuda, Takuya Morimoto, Hiroshi Shimizu, "Bacterial cell factory for production of scyllo-inositol, a potential therapeutic agent for Alzheimer's disease", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014
  14. Katsunori Yoshikawa, Kenichi Ogawa, Hiroshi Shimizu, "Development and analysis of high-light tolerant strain of Synechocystis sp. PCC 6803", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014
  15. Fumio Matsuda, Jun Ishii, Syunsuke Nishino, Keisuke Morita, AkihikoKondo, Hiroshi Shimizu, "Metabolic engineering of yeast centralmetabolism for higher alcohol production", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014
  16. Hiroshi Shimizu, "Integration of in silico Design and Experimental Evaluation for Creation of Microbial Cell Factories", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014, invited
  17. Kento Tokuyama, Satoshi Ohno, Katsunori Yoshikawa, Takashi Hirasawa, Shotaro Tanaka, Chikara Furusawa, Hiroshi Shimizu, "Increased 3-hydroxypropionic acid production from glycerol based on the genome-scale metabolic simulation in Escherichia coli", Metabolic Engineering X, Vancouver, Canada, Jun 15-19,2014
  18. Nobuyuki Okahashi, Katsunori Yoshikawa, Yoshiko Matsumoto, Tomokazu Shirai, Fumio Matsuda, Takashi Hirasawa, Chikara Furusawa, Mitsufumi Wada, Hiroshi Shimizu, "Metabolic Flux Analysis of Isopropyl Alcohol-Producing Escherichia coli", Metabolic Engineering X, Vancouver, Canada, Jun 15-19, 2014
  19. Fumio Matsuda, "Integration of metabolomic and proteomic profiling of central carbon metabolism in microbial cell factories", Special Workshop for NSF-JST cpllabolation on Metabolomics for Low Carbon Society, UCLA NanoSystem Institute Auditorium, Jun 4-5,2014
  20. Hiroshi Shimizu, "Computational design and experimental evaluation of microbial cell factories", Special Workshop for NSF-JST cpllabolation on Metabolomics for Low Carbon Society, UCLA NanoSystem
    Institute Auditorium, Jun 4-5,2014
  21. Hiroshi Shimizu, "Integration of in silico and Experimental Approaches for Creation of Microbial Cell Factories", 2014 KSBB Spring Meeting and International Symposium, A105, Hyundai Hotel, Gyeongju, Korea Apr 9-11, 2014, invited

2013

  1. Katsunori Yoshikawa,"Multi-omics analysis of high-light tolerant strain of Synechocystics sp. PCC6803", Asian Congress on Biotechnology 2013, Indian Institute of Technology Delhi, Dec 15-19, 2013
  2. Yoshihiro Toya,"13 C-Metabolic flux analysis for cellulase production by Bacillus subtilis genome-reduced strain", Asian Congress on Biotechnology 2013, Indian Institute of Technology Delhi, Dec 15-19, 2013
  3. Hiroshi Shimizu, "Systems metabolic engineering - Rational design of microbial cell factories", Asian Congress on Biotechnology 2013, Indian Institute of Technology Delhi, Dec 15-19, 2013
  4. Katsunori Yoshikawa,"Toward systems metabolic engineering of cyanobacteria",1st Korea-Japan Microalgae Symposium, KAIST, Oct 10-12,2013Takashi Hirasawa, Masaki Saito, Chikara Furusawa, Hiroshi shimizu,"GENOME-WIDE GENE EXPRESSION ANALYSIS OF CORYNEBACTERIUM GLUTAMICUM DURING PENICILLIN-INDUCED GLUTAMIC ACID PRODUCTION", Genetics of Industrial Microorganisms(GIM-2013), Cancun Convention Center, Cancun, Mexico, Jun 23-28, 2013
  5. Hiroshi Shimizu, "International collaborative research on systems metablic engineering for low carbon society",  Biochemical and Molecular engineering XVⅢ, Beijing Pharma and Biotech Center, Beijing, China, Jun 19, 2013, invited

 2012

  1. Nobuyuki Okahashi, Shuichi Kajihata, Chikara Furusawa, Fumio Matsuda, Akihiko Kondo and Hiroshi Shimizu, "Development and verification of metabolic flux analysis based on isotopomer enrichment of intermediate metabolites", The 23rd International Conference on Genome Informatics(GIW2012), National Cheng Kung University, Tainan City, Taiwan, Dec 12-14, 2012
  2. Eiji Mori, Shuichi Kajihata, Yuki Usui, Takashi Hirasawa, Chikara Furusawa and Hiroshi Shimizu, "Analysis of metabolic shift in pgi expression-controlled Escherichia coli using labeling information of intermediate metabolites", Foundations of Systems Biology in Engineering (FOSBE 2012), The Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, Oct 21-25, 2012
  3. Hiroshi shimizu, "Application of Genome Scale Models to Design of Microbial Cell Factories",  2nd Conference on Constraint-based Reconstruction and Analysis (COBRA 2012), Hotel Marienlyst, Helsingor, Denmark, Oct 7-9, 2012, invited
  4. Hiroshi shimizu, "Systems metabolic engineering for creation of superior microbial cell factories",  Systems Biotechnology of Microalgae for Bioproduction, International Symposium and Exhibition, (EXCO, Daegu, Korea, Sep 16-21, 2012
  5. Satoshi Ohno, Chikara Furusawa, Hiroshi Shimizu, "FastPros: Efficient screening algorithm of gene knockouts for useful compound production using genome-scale metabolic model", 10th KAIST-Osaka University Graduate Students Symposium, Korea Advanced Institute of Science and Technology(KAIST), Daejeon, Korea, Aug 6-8, 2012
  6. Shuichi kajihata, Chikara Furusawa, Hiroshi Shimizu,"Development of application software of 13C-based metabolic flux analysis", 10th KAIST-Osaka University Graduate Students Symposium, Korea Advanced Institute of Science and Technology(KAIST), Daejeon, Korea, Aug 6-8, 2012
  7. Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu,"Systems biology in Synechocystis sp. PCC 6803",Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre, Biarritz, France, Jun 3-7, 2012
  8. Sunisa Chatsurachai, Chikara Furusawa, Hiroshi Shimizu,"In silico platform for rational heterologous pathway design of nonnative metabolites using genome-metabolic networks information", Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre in Biarritz, France, Jun 3-7, 2012
  9. Tsubasa Nakajima, Shuichi Kajihata, Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu,"Metabolic flux analysis of cyanobacteria on various trophic conditions", Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre in Biarritz, France, Jun 3-7, 2012
  10. Satoshi Ohno, Chikara Furusawa, Hiroshi Shimizu, "FastPros: Screening method of multiple gene knockout for microbial production using genome-scale metabolic model", Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre in Biarritz, France, Jun 3-7, 2012 Student/Young Investigator Poster Award, Topical Area: System Biology and Metabolic Engineering
  11. Satoshi Ohno, Chikara Furusawa, Hiroshi Shimizu,"Systems biology in Synechocystis sp. PCC 6803", Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre in Biarritz, France, Jun 3-7, 2012
  12. Hiroshi Shimizu,"Genome-wide multi-omics analysis of ethanol stress tolerant strain of Escherichia coli created by evolution engineering", Metabolic Engineering IX, Le Bellevue Congress and Exhibition centre in Biarritz, France, Jun 3-7, 2012
  13. Hiroshi Shimizu,"Integration of in silico and experimental approaches for creation of microbial cell factories", 14th Asia Pacific Confederation of Chemical Engineering (APCChE 2012), Suntec Singapore International Convention & Exhibition Center, Singapore, Feb 21-24, 2012

2011

  1. Katsunori Yoshikawa, Yuta Kojima, Tsubasa Nakajima, Chikara Furusawa, Takashi Hirasawa, Hiroshi Shimizu,”Metabolic engineering using genome-scale metabolic model for improvement of photosynthetic bioproduction”,The 2nd iBioP Asian Symposium (iBioP2011), POSTECH (Pohang University of Science and Technology), Pohang, South Korea, Dec 14-16, 2011
  2. Hiroshi Shimizu, Chikara Furusawa, Takashi Hirasawa, Katsunori Yoshikawa, Naoaki Ono,"Genome Scale Metabolic Flux Design and Experimental Evaluation of Cellular Performance", The 2nd iBioP Asian Symposium (iBioP2011), POSTECH (Pohang University of Science and Technology), Pohang, South Korea, Dec 14-16, 2011
  3. Yoshihiro Ida, Takashi Hirasawa, Chikara Furusawa, Hiroshi Shimizu, "A computer-aided design of lactate production process using Saccharomyces cerevisiae",Genome Informatics Workshop2011(GIW2011), Haeundae Grand Hotel, Busan, South Korea, Dec 5-7, 2011
  4. Takaaki Horinouchi, Shingo Suzuki, Naoaki Ono, Kuniyasu Tamaoka, Takashi Hirasawa, Tetsuya Yomo, Hiroshi Shimizu, Chikara Furusawa, "Comprehensive analysis of evolution dynamics in Escherichia coli from parallel experimental evolutions under ethanol stress condition", International Symposium on SYNTHESIZING LIFE AND BIOLOGICAL SYSTEMS, Life Science Center, Osaka, Japan, Oct 24-26, 2011
  5. Shuichi kajihata, Chikara Furusawa, Hiroshi Shimizu, "Metabolic Flux meter(MFmeter): An Application to Construct Metabolic Models for 13C-tracer Metabolic Flux Analysis", International Union of Microbiological Societies 2011 Congress(IUMS2011), Sapporo Convention Center, Hokkaido, Japan, Sep 6-10, 2011
  6. Sunisa Chatsurachai, Chikara Furusawa, Hiroshi Shimizu, "In Silico Platform for Heterologous Pathway Design to Produce Non-native Metabolites", International Union of Microbiological Societies 2011 Congress(IUMS2011), Sapporo Convention Center, Hokkaido, Japan, Sep 6-10, 2011
  7. Tsubasa Nakajima, Shuichi kajihata, Yuta Kojima, Katsunori Yoshikawa, Takashi Hirasawa, Chikara Furusawa, and Hiroshi Shimizu, "Effect of a Photosynthesis Inhibitor on Metabolic Flux Profile of Cyanobacterium Synechocystis sp. PCC 6803", International Union of Microbiological Societies 2011 Congress(IUMS2011), Sapporo Convention Center, Hokkaido, Japan, Sep 6-10, 2011
  8. Takashi Hirasawa, Aki Ookubo, Masakado Takekuni, Katsunori Yoshikawa, Chikara Furusawa, and Hiroshi Shimizu, "Genome-Wide Identification of the Genes Related to L-lactate Production by the Recombinant Saccharomyces cerevisiae Strains",  International Union of Microbiological Societies 2011 Congress(IUMS2011), Sapporo Convention Center, Hokkaido, Japan, Sep 6-10, 2011
  9. Hiroshi Shimizu, "Systems Metabolic Engineering for Bioproduction Development",  International Union of Microbiological Societies 2011 Congress(IUMS2011), Sapporo Convention Center, Hokkaido, Japan, Sep 6-10, 2011
  10. Chikara Furusawa, Takaaki Horinouchi, Shingo Suzuki, Naoaki Ono, Kuniyasu Tamaoka, Takashi Hirasawa, Tetsuya Yomo, and Hiroshi Shimizu, "Genome-Wide resequencing and expression analyses of evolved Escherichia Coli strains under ethanol stress", Society for Molecular Biology and Evolution(SMBE2011), Kyoto University, Kyoto, Japan, Jul 26-30, 2011
  11. Katsunori Yoshikawa, Chikara Furusawa, Takashi Hirasawa and Hiroshi Shimizu, "Metabolic engineering using genome-scale metabolic model for superior cell factories", SIM Annual Meeting and Exhibition(SIM2011), Sheraton New Orleans, New Orleans, LA, USA, Jul 24-28, 2011
  12. Eiji Mori, Chikara Furusawa and Hiroshi Shimizu, "Metabolic Flux Analysis Based On 13C Labeling Pattern of Intracellular Amino Acids in Escherichia Coli", Asian Congress on Biotechnology(ACB-2011), Shanghai Everbright Convention & Exhibition Centre (SECEC), Shanghai, China, May 11-15, 2011
  13. Katsunori Yoshikawa, Yuta Kojima, Chikara Furusawa, Takashi Hirasawa and Hiroshi Shimizu, "Metabolic Flux Prediction by Genome-Scale Metabollic Model of Synechocystis sp. PCC6803", Asian Congress on Biotechnology(ACB-2011), (Shanghai Everbright Convention & Exhibition Centre (SECEC), Shanghai, China, May 11-15, 2011, ACB-2011 YYS(Young Scienist and Student) Outstanding Award
  14. Naoaki Ono, Chikara Furusawa, Takaaki Horinouchi, Kuniyasu Tamaoka, Shingo Suzuki, Takashi Hirasawa, Tetsuya Yomo and Hiroshi Shimizu, "Genome-Wide Mutational and Expression Analyses of Evolved Escherichia Coli Strains under Ethanol Stress", Asian Congress on Biotechnology(ACB-2011), Shanghai Everbright Convention & Exhibition Centre (SECEC), Shanghai, China, May 11-15, 2011
  15. Hiroshi Shimizu, "Omics Approach to Improve Performance of Microbial Cell Factory", Asian Congress on Biotechnology(ACB-2011), Shanghai Everbright Convention & Exhibition Centre (SECEC), Shanghai, China, May 11-15, 2011
  16. Hiroshi Shimizu, "Systems Metabolic Engineering for Bioproduction", Technical seminar on Bio-Technology in Japan and the Netherlands , Kobe University, hyogo, Japan, Feb 1, 2011

2010

  1. Yoshihiro Ida, Takashi Hirasawa, Chikara Furusawa, and Hiroshi Shimizu, "Prediction and Experimental Evaluation of Metabolic Profiles Using a Genome-Scale Metabolic Model of Saccharomyces cerevisiae",  The 21th International Conference on Genome Informatics(GIW 2010), The First World Hotel. Hangzhou, China, Dec 16-18, 2010
  2. Chikara Furusawa, Kota Ijichi and Hiroshi Shimizu, "Fluctuation-driven Adaptation and Symbiosis in Cellular Dynamics", 1st Workshop on Bio-inspired Models and Technologies for Ambient Information Society (BioAmbIS 2010), Le Meridien Cambridge Hotel, Boston, USA, Dec 1-3, 2010
  3. Sunisa Chatsurachai , Chikara Furusawa, Hiroshi Shimizu, "De novo Pathway Design Platform for Exploring Biosynthetic Capacity in Genome Scale Model of Microorganisms as Cell Factories",  9th International Conference on Bioinformatics (InCoB2010) (The official conference of the Asia-Pacific Bioinformatics Network), International Conference Center (ICC), Waseda University, Tokyo, Japan, Sep 26-28, 2010 InCoB2010 Best Poster Award受賞
  4. Hiroshi Shimizu,"Systems Metabolic Engineering for Creation of Cell Factory", Peking University-Osaka University Academic Exchange Day, Seminar at School of Life Sciences, Beijing University, Beijing, China, Sep 19-21, 2010
  5. Hiroshi Shimizu, "Systems biotechnology for creation of microbial cell factroy", 2010 International Symposium on Advanced Biological Engineering(ISABE'2010), Beijing Friendship Hotel, Beijing, China, Jul 23-25, 2010
  6. Yoshihiro Ida, "Construction and Analysis of alcohol dehydrogenase-negative yeast based on genome scale metabolic model", 2010 KAIST - Osaka University Graduate Students Symposium In Biotechnology, Okuike lodge, Hyogo, Japan, Jul 22-24, 2010
  7. Takashi Hirasawa, Chikara Furusawa, Hiroshi Shimizu, "Transcriptome and phenome analyses of Saccharomyces cerevisiae for identifying the important genes to confer ethanol stress tolerance", 11th International Symposium on the Genetics of Industrial Microorganisms (GIM2010), Melbourne Convention and Exhibition Centre, Melbourne, Australia, Jun 28-Jul 1, 2010
  8. Hiroshi Shimizu,"(Session 7)Emerging Tools and Methods in Metabolic Engineering",Metabolic Engineering VIII,International Convention Center Jeju, Jeju Island, South Korea, Jun 13-18, 2010
  9. Chikara Furusawa, "Genome-wide analysis of ethanol stress tolerant strains of Escherichia Coli obtained by evolution experiments", Metabolic Engineering VIII, International Convention Center Jeju, Jeju Island, South Korea, Jun 13-18, 2010
  10. Chikara Furusawa, Yuta Kojima,Takashi Hirasawa, Naoki Ono, Tsubasa Nakajima, Hiroshi Shimizu, "Development and Experimental Verification of a Genome-Scale Metabolic Model for Synechocystis sp. PCC6803", International Symposium on Microalgal Biotechnology-Food・Environment・Energy, The University of Tokyo, Japan, May 31, 2010

2009

  1. Takaaki Horinouchi, Kuniyasu Tamaoka, Chikara Furusawa, Takashi Hirasawa, Naoaki Ono, Shingo Suzuki, Tetsuya Yomo, and Hiroshi Shimizu, "Genome-Wide Mutational and Expression Analyses of Evolved Escherichia Coli Strains Under Ethanol Stress", The 20th International Conference on Genome Informatics(GIW 2009), Pacifico Yokohama, Japan, Dec 14-16, 2009
  2. Chikara Furusawa, "Development Of Physico-Chemical Model Of Hybridization For High-Resolution Microarray Analysis", BIT's 3rd World Congress of Gene-2009(WCG-2009), Golden Sun Hotel, Foshan, China, Dec 2, 2009
  3. Siraje Arif Mahmud, Takashi Hirasawa, and Hiroshi Shimizu, "High constitutive trehalose is required for resistance to multiple stresses in Saccharomyces cerevisiae", Asia Pacific Biochemical Engineering Conference 2009(APBioChEC'09), Kobe International Conference Center Port Island, Kobe, Japan, Nov 25, 2009
  4. Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, and Tetsuya Yomo, "A model-based analysis method for detection of single-base substitution using resequencing microarrays", Asia Pacific Biochemical Engineering Conference 2009(APBioChEC'09), Kobe International Conference Center Port Island, Kobe, Japan, Nov 25, 2009
  5. Chikara Furusawa, Yohei Shinfuku, Natee Sorpitiporn, Masahiro Sono, Takashi Hirasawa, and Hiroshi Shimizu, "Flux balance analysis of Corynebacterium glutamicum using a genome-scale metabolic model",  Asia Pacific Biochemical Engineering Conference 2009(APBioChEC'09), Kobe International Conference Center Port Island, Kobe, Japan, Nov 26, 2009
  6. Hiroshi Shimizu, "Multiomics analyses for identification of important genes under stress conditions in bioprocesse", Asia Pacific Biochemical Engineering Conference 2009(APBioChEC'09), Kobe International Conference Center Port Island, Kobe, Japan, Nov 26, 2009
  7. Takaaki Horinouchi, Kuniyasu Tamaoka, Chikara Furusawa, Takashi Hirasawa, Naoaki Ono, Shingo Suzuki, Tetsuya Yomo, Hiroshi Shimizu, "Genome-wide mutational and expression analysis of ethanol-tolerant Escherichia coli", International Symposium on Complex Systems Biology (CSB2009), Tetsumon Memorial Hall, The University of Tokyo, Tokyo, Japan, Sep 30, 2009
  8. Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, Tetsuya Yomo, "Development of a thermodynamic model to predict hybridization on high-density oligonucleotide microarray",  International Symposium on Complex Systems Biology (CSB2009), Tetsumon Memorial Hall, The University of Tokyo, Tokyo, Japan, Sep 30, 2009
  9. Chikara Furusawa, "A Dynamic Model for Irreversible Differentiation in a Stem Cell System:Chaos Hypothesis", International Symposium on Complex Systems Biology (CSB2009), Tetsumon Memorial Hall, The University of Tokyo, Tokyo, Japan, Sep 30, 2009
  10. Chikara Furusawa, Kunihiko Kaneko, "Systems Biology approach for irreversible differentiation in a stem cell system: chaos hypothesis", The 10th International Conference on Systems Biology, Stanford, California, USA, Aug 30-Sep 4, 2009

2008

  1. Hiroshi Shimizu, Yohei Shinfuku, Masahiro, Sono, Chikara Furusawa, Takashi Hirasawa, "Metabolic Flux Balance Analysis of an Industrially Useful Microorganism Corynebacerium glutamicum by A Genome-Scale Reconstructed Model", The 3rd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems (BIONETICS2008),  Hyogo, Japan, CD-ROM,  Nov 25-28, 2008
  2. Chikara Furusawa, Kunihiko Kaneko, Hiroshi Shimizu, "A noise-driven mechanism for adaptive growth rate regulation",1st International Workshop on Technologies for Ambient Information Society(TAIS2008),  Hyogo, Japan, CD-ROM, Nov 25-28, 2008
  3. Naoaki Ono, Shingo Suzuki, Chikara Furusawa, Hiroshi Shimizu, Tetsuya Yomo, "Quantitative expression analysis using oligonucleotide microarrays based on a physico-chemical model",  The 3rd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems (BIONETICS2008),  Hyogo, Japan, CD-ROM, Nov 25-28, 2008
  4. Chikara Furusawa, Kunihiko Kaneko,"Theory of Irreversible Differentiation in a Stem Cell System: Chaos Hypothesis", The 23rd Naito conference on Molecular Basis for Maintenance and Differentiation of Stem Cells [III],  Zushi, Japan, PS-63, Nov 11-14, 2008
  5. Jongpill Kim, Takashi Hirasawa, Yoshiyasu Sato, Keisuke Nagahisa, Chikara Furusawa, Hiroshi Shimizu, "Modulation of 2-Oxoglutarate Dehydrogenase Complex Specific Activity by odhA Overexpression and odhA Antisense RNA Expression on Tween 40-triggered Glutamate Production in Corynebacterium glutamicum", 2008 International Meeting of the Federation of Korean Microbiologist Societies, Seoul, Korea, p.203, Oct 15-18, 2008
  6. Hiroshi Shimizu, Chikara Furusawa, Takashi Hirasawa, "Systems biotechnology of coryneform bacteria", The 13th international Biotechnology Symposium and Exhibition (IBS2008), Vol.136S, p.S100 Dalian, China, Oct 12-17, 2008
  7. Katsunori Yoshikawa, Tadamasa Tanaka, Chikara Furusawa, Keisuke Nagahisa, Takashi Hirasawa, Hiroshi Shimizu, "Comprehensive phenotypic analysis of yeast under ethanol stress condition", The 13th international Biotechnology Symposium and Exhibition (IBS2008), Dalian, China, Vol.136S, p.S111, Oct 12-17, 2008
  8. Takaaki Horinouchi, Katsunori Yoshikawa, Chikara Furusawa, Yoshihiro Nakao, Hiroshi Shimizu, "Analysis of lager brewing yeast at low temperature fermentation using DNA microarray", The 13th international Biotechnology Symposium and Exhibition(IBS2008), Dalian, China, Vol.136S, p.S351 Oct 12-17, 2008
  9. Hiroshi Shimizu, Katsunori Yoshikawa, Tadamasa Tanaka, Chikara Furusawa, Keisuke Nagahisa,"Comprehensive phenotypic analysis for identification of genes affecting growth under stress condition in bioprocesses", METABOLIC ENGINEERING VII, CasaMagna Marriott Puerto Vallarta Resort, Puerto Vallarta, Mexico, Sep 14-18, 2008

2007

  1. Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Katsunori Yoshikawa, Chikara Furusawa, Suteaki, Shioya, "Molecular Breeding based on Multi-Omics Analyses",  Asia Pacific Biochemical Engineering 2007, CD-ROM, Nov 4-8, 2007
  2. Hiroshi Shimizu,"Bionetwork following Power Laws", BIONETICS 2007, 2nd International Conference on Bio-Inspired Models of Network, Information, and Computing Systems, Radisson SAS Beke Hotel, Budapest, Hungary,Dec 10-13, 2007
  3. Nobuyoshi Ishii, Kenji Nakahigashi, Tomoya Baba, Martin Robert, Tomoyoshi Soga, Akio Kanai, Takashi Hirasawa, Miki Naba, Kenta Hirai, Aminul Hoque, Pei Yee Ho, Yuji Kakazu, Kaori Sugawara, Saori Igarashi, Satoshi Harada, Takeshi Masuda, Naoyuki Sugiyama, Takashi Togashi, Miki Hasegawa, Yuki Takai, Katsuyuki Yugi, Kazuharu Arakawa, Nayuta Iwata, Yoshihiro Toya, Yoichi Nakayama, Takaaki Nishioka, Kazuyuki Shimizu, Hirotada Mori, Masaru Tomita,"Multi-omics data reveals the response of Escherichia coli to perturbations", The eighth international conference on systems biology (ICSB2007), Long Beach, California, USA, Oct 1-6, 2007
  4. Tadashi Yamada, Chikara Furusawa, Testuya Yomo, Hiroshi Shimizu,"Analysis of the relationship between noise in gene expression and regulatory structure in amino acid biosynthesis pathways", The eighth international conference on systems biology (ICSB2007), Long Beach, California, USA, Oct 1-6, 2007
  5. Chikara Furusawa, Kunihiko Kaneko,"A generic mechanism for adaptive growth rate regulation by noise", The First q-bio conference, Santa Fe, New Mexico, USA, Aug 8-11, 2007
  6. Katsunori Yoshikawa, Tadamasa Tanaka, Keisuke Nagahisa, Chikara Furusawa, Hiroshi Shimizu, "Integration analysis of phenome and transctiptome in yeast under stress conditions", 23rd International Conference on Yeast Genetics and Molecular Biology, Vol.24, Issue S1, p.S140, Jul 13-34, 2007
  7. Hiroshi Shimizu, Takashi Hirasawa, Katsunori Yoshikawa, Yuki Nakakura, Keisuke Nagahisa, Chikara Furusawa, Yoshio Katakura, Suteaki Shioya, "Inverse metabolic engineering by integration of multiple omics analyses", 10th Computer Applications in Biotechnology (CAB10), Vol.1, p.15-20,  Jun 4-6, 2007
  8. Chikara Furusawa, Kunihiko Kaneko,"Universal Statistics for Chemical Abundances in Reproducing Cell", Journal of Korean Physical Society, Apr, 2007

2006

  1. Makoto Sadamitsu, Chikara Furusawa, Keisuke Nagahisa, Akiko Kashiwagi, Tetsuya Yomo and Hiroshi Shimizu, "Heterogeneity of cell population in continuous culture of Escherichia coli",  EABS & BSJ 2006 Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan,  Okinawa Convention center, Japan, 1P402, p. S247, Nov 12-16, 2006
  2. Tomoharu Hogiri, Naoaki Ono, Chikara Furusawa, Hiroshi Shimizu, "Relationship between Evolutionary Dynamics and Preservation of Molecular Structures in Metabolic Network", EABS & BSJ 2006 Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, 2P480, p.S415, Okinawa Convention center, Japan, Nov 12-16, 2006
  3. Hiroshi Shimizu, ”Design of strain improvement based on DNA Microarray data analysis of Saccharomyces cerevisiae”,  Metabolic Engineering Conference VI, p.40, The Netherlands, Oct 1-5, 2006
  4. Katsunori Yoshikawa, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, Hiroshi Shimizu, ”Extraction of the relationship between the gene expression and phenotype for breeding cell”, 20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress, Kyoto, Jun 18-23, 2006

2005

  1. Katsunori Yoshikawa, Gaurav Pandey, Takashi Hirasawa, Yoshio Katakura, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, Hiroshi Shimizu, "Molecular breeding of osmotic stress tolerant yeast strains based on clustering analysis of gene expression", Proceedings of Asia Pacific Biochemical Engineering ’05 (APBioChEC05), Jeju, Korea, P3-081, 4 pages, May 15-19, 2005
  2. Suteaki Shioya, Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Yoshio Katakura, "Metabolic Pathway Recruiting through Genomic Data Analysis of Saccharomyces cerevisiae",Proceedings of Asia Pacific Biochemical Engineering ’05 (APBioChEC05), Jeju, Korea, P3-085(PLA) 4pages, May 15-19, 2005
  3. Tomokazu Shirai, Kunihiro Matsuzaki, Yoshiyasu Sato, Masanori Kuzumoto, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, Hiroshi Shimizu, "Development of a metabolic flux distribution analysis method by integrating two dimensional NMR and GC-MS Data", Proceedings of Asia Pacific Biochemical Engineering ’05 (APBioChEC05), P3-085(PLA) 4pages, Jeju, Korea, May 15-19, 2005
  4. Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, "Analysis of multidimensional hierarchical bionetworks and systematic design of metabolic pathways for bioproduction", Proceedings of Asia Pacific Biochemical Engineering ’05 (APBioChEC05), SYS1-02 4pages, Jeju, Korea, May 15-19, 2005

2004

  1. Takashi Hirasawa, Katsunori Yoshikawa, Kengo Ashitani, Keisuke Nagahisa, Chikara, Furusawa, Yoshio Katakura, Hiroshi Shimizu and Suteaki Shioya, "Rational design for molecular breeding of industrially useful strains based on bioinformatic data in Saccharomyces cerevisiae" The 15th international conference on genome informatics, P047-1-2, Yokohama, Japan, Dec, 2004
  2. Suteaki Shioya, Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Yoshio Katakura, Chikara Furusawa, "Metabolic pathway recruiting through modeling of Saccharomyces cerevisiae based on genomics for industrial application", Proceeding of Asia Pacific Confederation of Chemical Engineering Conference (APCChE04), 2L-03, 10 pages, Kitakyushu, Oct 17-21, 2004
  3. Tomokazu Shirai, Masanori Kuzumoto, Kunihiro Matsuzaki, Yoshiyasu Satou, Keisuke Nagahisa, Chikara Furusawa, Hiroshi Shimizu, and Suteaki Shioya, "Metabolic flux analysis in two kinds of coryneform bacteria with GC-MS and NMR", Proceeding of Asia Pacific Confederation of Chemical Engineering Conference (APCChE04),x(3P-01-52), 10 pages, Kitakyushu, Oct 17-21, 2004
  4. Michiko Kobayashi, Keisuke Nagahisa, Hiroshi Shimizu, Suteaki Shioya, "Simultaneous control of apparent extract and volatile compounds concentrations in a beer brewing process", Proceeding of Asia Pacific Confederation of Chemical Engineering (APCChE04), 3P-01-064, 10 pages, Kitakyushu, Oct 17-21, 2004
  5. Tadashi Yamada, Kouichi.Maeoka, Akiko Kashiwagi, Keisuke Nagahisa, Chikara.Furusawa, Suteaki.Shioya, TetsuyaYomo, Hiroshi Shimizu, "Analysis of Cell Population Dynamics in Continuous Culture of Escherichia coli", Proceeding of Asia Pacific Chemical Engineering Conference (APCChE04), 3P-01-087, 6 pages, Kitakyushu, Oct 17-21, 2004
  6. Keisuke Nagahisa, Kazuyuki Yamada, Yuki Nakakura, Takashi Hirasawa, Yoshio Katakura, Hiroshi Shimizu, Suteaki Shioya, "Analysis of adaptation of yeast cells to a high osmotic pressure stress based on proteomics", Proceeding of Asia Pacific Confederation of Chemical Engineering (APChE04), 3L-08, 7 pages, Kitakyushu, Oct 17-21, 2004
  7. Katsunori Yoshikawa, Gaurav Pandey, Takashi Hirasawa, Yoshio Katakura, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, Hiroshi Shimizu, "Analysis of DNA microarray data using Self-Organizing Map and hierarchical clustering", Proceeding of Asia Pacific Confederation of Chemical Engineering (APCChE04), 3P-01-055, 10 pages, Kitakyushu, Oct 17-21, 2004
  8. Takashi Hirasawa, Yuki Nakakura, Zhao Hui, Keisuke Nagahisa, Yoshio Katakura, Hiroshi Shimizu, Suteaki Shioya, "Rational design of metabolic pathway improvement based on DNA microarray data in yeast", Proceeding of Asia Pacific Confederation of Chemical Engineering (APChE04), (2L-09) , 10 pages, Kitakyushu, Oct 17-21, 2004
  9. Hiroshi Shimizu, Tomokazu Shirai, Masanori Kuzumoto, Takashi Hirasawa, Yoshio Katakura, Keisuke Nagahisa, Chikara Furusawa, and Suteaki Shioya, "Metabolic systems analysis at a key branch point of glutamate production by coryneform bacteria", Proceeding of Asia Pacific Confederation of Chemical Engineering (APCChE04), (2L-10), 10 pages, Kitakyushu, Oct 17-21, 2004
  10. Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Chikara Furusawa, Yoshio Katakura and Suteaki Shioya, "Rational improvement strategy of metabolic pathway based on bioinformatic data in Saccharomyces cerevisiae", Metabolic Engineering p. 20,V, Lake Tahoe, Sept 19-23 2004
  11. Michiko Kobayashi, Toshinari Hiroshima, Hiroshi Shimizu, Suteaki Shioya,"Simultaneous control of apparent extract and volatile compounds concentrations in a beer fermentation process",9th  International Symposium on Computer Applications in Biotechnology (CAB9), Nancy, France, Mar 28-31 2004
  12. ihua Huang, Hiroshi Shimizu, Suteaki Shioya,"Gene network analysis by a self organizing map and an artificial neural network",9th  International Symposium on Computer Applications in Biotechnology (CAB9), Nancy, France, Mar 28-31 2004
  13. Hiroshi Shimizu, Takashi Hirasawa, Keisuke Nagahisa, Suteaki Shioya,"Analysis of responses of complex bionetworks to changes in environmental conditions", The First International Workshop on Biologically Inspired Approaches to Advanced Information Technology, Swiss Federal Institute of Technolory, Lausanne, Switzerland, Jan 29-30
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